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What is this vaccine against covid-19?

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By Dr. Kavindya Marapana

COVID-19 has impacted millions of lives worldwide. Sri Lanka reported its first case of COVID-19 on 27thJanuary 2020 and since then the epidemic has affected Sri Lanka significantly, especially since the second wave of COVID-19 in October 2020, causing a severe health, economic and social burden. Globally, whilst many people may have asymptomatic infection, around 40% of the infected persons develop a range of mild symptoms which include fever, a new and continuous cough, shortness of breath, sore throat, fatigue, loss of appetite, diarrhoea, etc. Only around 15% of the patients develop severe complications such as pneumonia, and out them around 5% suffer from life-threatening diseases including severe respiratory distress syndrome, thromboembolic events and multi-organ failure. In Sri Lanka, 79, 999 cases have been identified to the date of writing and although the incidence of COVID-19 related complications seem to be low, 445 deaths have been reported up-to-date, including paediatric deaths. COVID -19 is also believed to have long-term effects on neurological system which is still in research stage.

The Ministry of Health has introduced a Covid-19 vaccine, which is considered safe and efficacious as evident from the available information about vaccine trials. Given the high priority requirement of safeguarding essential healthcare facilities of the country, adhering to global Covid-19 vaccination prioritization guidelines and recommendations by the National Advisory Committee of Communicable Diseases, healthcare staff and other support frontline workers have been inoculated.

Over 280 different COVID-19 vaccines are at various stages of development. Some have been made with the help of currently available vaccine technology, and completely new approaches have been adopted in producing others. While it normally takes several years to develop a vaccine, scientists across the world have worked collaboratively and expeditiously to achieve the same amount of work in a few months to make a safe and effective vaccine available as soon as possible. Although clinical trials have been carried out more rapidly than they have for other vaccines, this has been achieved by conducting some of the steps in parallel rather than sequentially and vaccine safety has not been compromised.

With the initiation of the vaccination programme in Sri Lanka, lot of questions have been raised by the public and we believe to answer a few common questions that have been raised frequently with the expertise of Dr. Chintha Karunasekara, Consultant Microbiologist at Lady Ridgeway Hospital for Children.

 

What is the vaccine given to
the Sri Lankans at the moment?

It is the COVISHIELD vaccine made by the Serum Institute of India (SII) that is brought down to Sri Lanka as the first batch of vaccines against corona virus. It is the same vaccine as the COVID-19 Vaccine AstraZeneca (ChAdOx1nCoV-19 Corona Virus Vaccine-Recombinant) developed by the University of Oxford but is developed to be effective at the temperatures of South Asian countries.

 

How does it protect me against COVID-19?

It is a viral vector vaccine, which uses a safe, weakened virus (adenovirus) which does not have the ability to multiply inside the body. It is genetically engineered to include a protein of SARS-C0V-2 (SARS-Cov-2 spike S) which triggers an immune response in the body against the COVID-19 virus, which protects the body from the possibility of developing disease or severe disease leading to death. The virus in the vaccine is destroyed after introducing the protein in the body. After the first dose of vaccine, the second dose is recommended to be taken in four weeks time. But the latest studies are recommending to increase the gap between the two doses up to 12 weeks for increased efficacy. The duration of protection by the vaccine is still not confirmed and is currently being studied. Therefore, with the current data it may require for it to be repeated yearly.

 

Is it safe for me to take it?

The COVID-19 vaccine AstraZeneca is currently under phase 3 vaccine trials and is found to be the most safe and efficacious vaccine among the vaccines currently being used. But there are instances where the vaccination should be strictly avoided and informed to the vaccination team without hesitance;

Known allergic reactions to the constituents of the COVISHIELD vaccine (L-Histidine, L-Histidine hydrochloride monohydrate, Magnesium chloride hexahydrate, Polysorbate 80, Ethanol, Sucrose, Sodium chloride, Disodium edetatedihydrate (EDTA), Water for injection)

History of severe allergic reactions leading to hospital admission or anaphylaxis.

Pregnancy , lactation and in children less than 18 years (not enough evidence is still available for the safe use of the vaccine among these groups)

Special precautions are to be taken if you are having a disease affecting bleeding and coagulation.

There are special situations where the vaccination is to be postponed for 4 to 8 weeks, and those are;

If you have any symptoms suggestive of COVID-19.

If you are suffering from an acute illness and not fit for the vaccination.

If you are already diagnosed with COVID-19 and received anti-CoV 2 monoclonal antibodies or convalescent plasma as a treatment option.

Being under regular treatment for long term diseases is not a reason to avoid the vaccine. But those conditions must be communicated to the doctor prior to the vaccination.

 

Why should I take it? Can I still be protected against COVID-19 without the vaccine?

Vaccination is one of the powerful public health interventions to combat this pandemic. Two key reasons to take the vaccine are to protect ourselves and to protect those around us. After vaccination most are protected from disease and severe disease. Vaccination curbs the spread of the virus by reducing the number of infections in a population.

The more people are immunized, the better the chances of reaching herd immunity. Herd immunity is even unvaccinated people in a population can be protected from a certain virus, like COVID-19, if a certain threshold of vaccination is reached in that population. Likewise, vaccines protect individuals, also protect communities.

 

Does it protect me for lifetime?

Once an individual is vaccinated, how long will their immunity to Covid-19 last? To answer this question more data from vaccine trials have been collecting and it depends on how a vaccine performs and how SARS-CoV-2 acts in the real world. For more longer immunity may need a booster vaccine.

 

Can I still transmit the disease to
those who are around me?

Vaccines are typically designed to prevent people from getting sick with the virus, but it is not yet clear if the COVID-19 vaccines can stop you from transmitting the virus to others. This is why is it important for people to continue taking precautions such as physical distancing, hand washing, wearing masks and avoiding gatherings, especially in poorly-ventilated spaces

But the most recent studies have shown the COVID-19 AstraZeneca vaccine to reduce the risk of transmission by 67%, which is a ray of hope that in the near future further developments would take place to further reduce the transmission.

The more people are immunized, the better the chances of reaching herd immunity.Herd immunity is when a population can be protected from a certain virus, like COVID-19, if a threshold of vaccination is reached

 

How bad can the side-effects be?

Around 75% of the healthcare personnel who received the vaccine reported to have mild to moderate symptoms as a result of the ongoing immune reaction following the vaccination. The most commonly reported symptoms were fever (low to high grade), chills, rigorus, muscle and joint pains, fatigue, lethargy, loss of appetite and vaccine site pain and swelling.

Less commonly abdominal pain, minor allergic reactions, enlarged lymph nodes have been reported but severe allergic reactions, anaphylaxis have not been reported so far in Sri Lanka.

The vaccination programme which is started by the government with the frontline healthcare workers is now started in stages to reach the rest of the population in Sri Lanka and the type of vaccine could be different to COVISHIELD, which we hope to write about in the future.

 

 


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Islamophobia and the threat to democratic development

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There’s an ill more dangerous and pervasive than the Coronavirus that’s currently sweeping Sri Lanka. That is the fear to express one’s convictions. Across the public sector of the country in particular many persons holding high office are stringently regulating and controlling the voices of their consciences and this bodes ill for all and the country.

The corrupting impact of fear was discussed in this column a couple of weeks ago when dealing with the military coup in Myanmar. It stands to the enduring credit of ousted Myanmarese Head of Government Aung San Suu Kyi that she, perhaps for the first time in the history of modern political thought, singled out fear, and not power, as the principal cause of corruption within the individual; powerful or otherwise.

To be sure, power corrupts but the corrupting impact of fear is graver and more devastating. For instance, the fear in a person holding ministerial office or in a senior public sector official, that he would lose position and power as a result of speaking out his convictions and sincere beliefs on matters of the first importance, would lead to a country’s ills going unaddressed and uncorrected.

Besides, the individual concerned would be devaluing himself in the eyes of all irrevocably and revealing himself to be a person who would be willing to compromise his moral integrity for petty worldly gain or a ‘mess of pottage’. This happens all the while in Lankan public life. Some of those who have wielded and are wielding immense power in Sri Lanka leave very much to be desired from these standards.

It could be said that fear has prevented Sri Lanka from growing in every vital respect over the decades and has earned for itself the notoriety of being a directionless country.

All these ills and more are contained in the current controversy in Sri Lanka over the disposal of the bodies of Covid victims, for example. The Sri Lankan polity has no choice but to abide by scientific advice on this question. Since authorities of the standing of even the WHO have declared that the burial of the bodies of those dying of Covid could not prove to be injurious to the wider public, the Sri Lankan health authorities could go ahead and sanction the burying of the bodies concerned. What’s preventing the local authorities from taking this course since they claim to be on the side of science? Who or what are they fearing? This is the issue that’s crying out to be probed and answered.

Considering the need for absolute truthfulness and honesty on the part of all relevant persons and quarters in matters such as these, the latter have no choice but to resign from their positions if they are prevented from following the dictates of their consciences. If they are firmly convinced that burials could bring no harm, they are obliged to take up the position that burials should be allowed.

If any ‘higher authority’ is preventing them from allowing burials, our ministers and officials are conscience-bound to renounce their positions in protest, rather than behave compromisingly and engage in ‘double think’ and ‘double talk’. By adopting the latter course they are helping none but keeping the country in a state of chronic uncertainty, which is a handy recipe for social instabiliy and division.

In the Sri Lankan context, the failure on the part of the quarters that matter to follow scientific advice on the burials question could result in the aggravation of Islamophobia, or hatred of the practitioners of Islam, in the country. Sri Lanka could do without this latter phobia and hatred on account of its implications for national stability and development. The 30 year war against separatist forces was all about the prevention by military means of ‘nation-breaking’. The disastrous results for Sri Lanka from this war are continuing to weigh it down and are part of the international offensive against Sri Lanka in the UNHCR.

However, Islamophobia is an almost world wide phenomenon. It was greatly strengthened during Donald Trump’s presidential tenure in the US. While in office Trump resorted to the divisive ruling strategy of quite a few populist authoritarian rulers of the South. Essentially, the manoeuvre is to divide and rule by pandering to the racial prejudices of majority communities.

It has happened continually in Sri Lanka. In the initial post-independence years and for several decades after, it was a case of some populist politicians of the South whipping-up anti-Tamil sentiments. Some Tamil politicians did likewise in respect of the majority community. No doubt, both such quarters have done Sri Lanka immeasurable harm. By failing to follow scientific advice on the burial question and by not doing what is right, Sri Lanka’s current authorities are opening themselves to the charge that they are pandering to religious extremists among the majority community.

The murderous, destructive course of action adopted by some extremist sections among Muslim communities world wide, including of course Sri Lanka, has not earned the condemnation it deserves from moderate Muslims who make-up the preponderant majority in the Muslim community. It is up to moderate opinion in the latter collectivity to come out more strongly and persuasively against religious extremists in their midst. It will prove to have a cementing and unifying impact among communities.

It is not sufficiently appreciated by governments in the global South in particular that by voicing for religious and racial unity and by working consistently towards it, they would be strengthening democratic development, which is an essential condition for a country’s growth in all senses.

A ‘divided house’ is doomed to fall; this is the lesson of history. ‘National security’ cannot be had without human security and peaceful living among communities is central to the latter. There cannot be any ‘double talk’ or ‘politically correct’ opinions on this question. Truth and falsehood are the only valid categories of thought and speech.

Those in authority everywhere claiming to be democratic need to adopt a scientific outlook on this issue as well. Studies conducted on plural societies in South Asia, for example, reveal that the promotion of friendly, cordial ties among communities invariably brings about healing among estranged groups and produces social peace. This is the truth that is waiting to be acted upon.

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Pakistan’s love of Sri Lanka

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By Sanjeewa Jayaweera

It was on 3rd January 1972 that our family arrived in Karachi from Moscow. Our departure from Moscow had been delayed for a few weeks due to the military confrontation between Pakistan and India. It ended on 16th December 1971. After that, international flights were not permitted for some time.

The contrast between Moscow and Karachi was unbelievable. First and foremost, Moscow’s temperature was near minus 40 degrees centigrade, while in Karachi, it was sunny and a warm 28 degrees centigrade. However, what struck us most was the extreme warmth with which the airport authorities greeted our family. As my father was a diplomat, we were quickly ushered to the airport’s VIP Lounge. We were in transit on our way to Rawalpindi, the airport serving the capital of Islamabad.

We quickly realized that the word “we are from Sri Lanka” opened all doors just as saying “open sesame” gained entry to Aladdin’s cave! The broad smile, extreme courtesy, and genuine warmth we received from the Pakistani people were unbelievable.

This was all to do with Mrs Sirima Bandaranaike’s decision to allow Pakistani aircraft to land in Colombo to refuel on the way to Dhaka in East Pakistan during the military confrontation between Pakistan and India. It was a brave decision by Mrs Bandaranaike (Mrs B), and the successive governments and Sri Lanka people are still enjoying the fruits of it. Pakistan has been a steadfast and loyal supporter of our country. They have come to our assistance time and again in times of great need when many have turned their back on us. They have indeed been an “all-weather” friend of our country.

Getting back to 1972, I was an early beneficiary of Pakistani people’s love for Sri Lankans. I failed the entrance exam to gain entry to the only English medium school in Islamabad! However, when I met the Principal, along with my father, he said, “Sanjeewa, although you failed the entrance exam, I will this time make an exception as Sri Lankans are our dear friends.” After that, the joke around the family dinner table was that I owed my education in Pakistan to Mrs B!

At school, my brother and I were extended a warm welcome and always greeted “our good friends from Sri Lanka.” I felt when playing cricket for our college; our runs were cheered more loudly than of others.

One particular incident that I remember well was when the Embassy received a telex from the Foreign inistry. It requested that our High Commissioner seek an immediate meeting with the Prime Minister of Pakistan, Mr Zulifikar Ali Bhutto (ZB), and convey a message from Mrs B. The message requested that an urgent shipment of rice be dispatched to Sri Lanka as there would be an imminent rice shortage. As the Ambassador was not in the station, the responsibility devolved on my father.

It usually takes about a week or more to get an audience with the Prime Minister (PM) of a foreign country due to their busy schedule. However, given the urgency, my father spoke to the Foreign Ministry’s Permanent Sectary, who fortunately was our neighbour and sought an urgent appointment. My father received a call from the PM’s secretary around 10 P.M asking him to come over to the PM’s residence. My father met ZB around midnight. ZB was about to retire to bed and, as such, was in his pyjamas and gown enjoying a cigar! He had greeted my father and had asked, “Mr Jayaweera, what can we do for great friend Madam Bandaranaike?. My father conveyed the message from Colombo and quietly mentioned that there would be riots in the country if there is no rice!

ZB had immediately got the Food Commissioner of Pakistan on the line and said, “I want a shipload of rice to be in Colombo within the next 72 hours!” The Food Commissioner reverted within a few minutes, saying that nothing was available and the last export shipment had left the port only a few hours ago to another country. ZB had instructed to turn the ship around and send it to Colombo. This despite protests from the Food Commissioner about terms and conditions of the Letter of Credit prohibiting non-delivery. Sri Lanka got its delivery of rice!

The next was the visit of Mrs B to Pakistan. On arrival in Rawalpindi airport, she was given a hero’s welcome, which Pakistan had previously only offered to President Gaddafi of Libya, who financially backed Pakistan with his oil money. That day, I missed school and accompanied my parents to the airport. On our way, we witnessed thousands of people had gathered by the roadside to welcome Mrs B.

When we walked to the airport’s tarmac, thousands of people were standing in temporary stands waving Sri Lanka and Pakistan flags and chanting “Sri Lanka Pakistan Zindabad.” The noise emanating from the crowd was as loud and passionate as the cheering that the Pakistani cricket team received during a test match. It was electric!

I believe she was only the second head of state given the privilege of addressing both assemblies of Parliament. The other being Gaddafi. There was genuine affection from Mrs B amongst the people of Pakistan.

I always remember the indefatigable efforts of Mr Abdul Haffez Kardar, a cabinet minister and the President of the Pakistan Cricket Board. From around 1973 onwards, he passionately championed Sri Lanka’s cause to be admitted as a full member of the International Cricket Council (ICC) and granted test status. Every year, he would propose at the ICC’s annual meeting, but England and Australia’s veto kept us out until 1981.

I always felt that our Cricket Board made a mistake by not inviting Pakistan to play our inaugural test match. We should have appreciated Mr Kardar and Pakistan’s efforts. In 1974 the Pakistan board invited our team for a tour involving three test matches and a few first-class games. Most of those who played in our first test match was part of that tour, and no doubt gained significant exposure playing against a highly talented Pakistani team.

Several Pakistani greats were part of the Pakistan and India team that played a match soon after the Central Bank bomb in Colombo to prove that it was safe to play cricket in Colombo. It was a magnificent gesture by both Pakistan and India. Our greatest cricket triumph was in Pakistan when we won the World Cup in 1996. I am sure the players and those who watched the match on TV will remember the passionate support our team received that night from the Pakistani crowd. It was like playing at home!

I also recall reading about how the Pakistani government air freighted several Multi Barrell artillery guns and ammunition to Sri Lanka when the A rmy camp in Jaffna was under severe threat from the LTTE. This was even more important than the shipload of rice that ZB sent. This was crucial as most other countries refused to sell arms to our country during the war.

Time and again, Pakistan has steadfastly supported our country’s cause at the UNHCR. No doubt this year, too, their diplomats will work tirelessly to assist our country.

We extend a warm welcome to Mr Imran Khan, the Prime Minister of Pakistan. He is a truly inspirational individual who was undoubtedly an excellent cricketer. Since retirement from cricket, he has decided to get involved in politics, and after several years of patiently building up his support base, he won the last parliamentary elections. I hope that just as much as he galvanized Sri Lankan cricketers, his political journey would act as a catalyst for people like Kumar Sangakkara and Mahela Jayawardene to get involved in politics. Cricket has been called a “gentleman’s game.” Whilst politics is far from it!.

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Covid-19 health rules disregarded at entertainment venues?

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Believe me, seeing certain videos, on social media, depicting action, on the dance floor, at some of these entertainment venues, got me wondering whether this Coronavirus pandemic is REAL!

To those having a good time, at these particular venues, and, I guess, the management, as well, what the world is experiencing now doesn’t seem to be their concerned.

Obviously, such irresponsible behaviour could create more problems for those who are battling to halt the spread of Covid-19, and the new viriant of Covid, in our part of the world.

The videos, on display, on social media, show certain venues, packed to capacity – with hardly anyone wearing a mask, and social distancing…only a dream..

How can one think of social distancing while gyrating, on a dance floor, that is over crowded!

If this trend continues, it wouldn’t be a surprise if Coronavirus makes its presence felt…at such venues.

And, then, what happens to the entertainment scene, and those involved in this field, especially the musicians? No work, whatsoever!

Lots of countries have closed nightclubs, and venues, where people gather, in order to curtail the spread of this deadly virus that has already claimed the lives of thousands.

Thailand did it and the country is still having lots of restrictions, where entertainment is concerned, and that is probably the reason why Thailand has been able to control the spread of the Coronavirus.

With a population of over 69 million, they have had (so far), a little over 25,000 cases, and 83 deaths, while we, with a population of around 21 million, have over 80,000 cases, and more than 450 deaths.

I’m not saying we should do away with entertainment – totally – but we need to follow a format, connected with the ‘new normal,’ where masks and social distancing are mandatory requirements at these venues. And, dancing, I believe, should be banned, at least temporarily, as one can’t maintain the required social distance, while on the dance floor, especially after drinks.

Police spokesman DIG Ajith Rohana keeps emphasising, on TV, radio, and in the newspapers, the need to adhere to the health regulations, now in force, and that those who fail to do so would be penalised.

He has also stated that plainclothes officers would move around to apprehend such offenders.

Perhaps, he should instruct his officers to pay surprise visits to some of these entertainment venues.

He would certainly have more than a bus load of offenders to be whisked off for PCR/Rapid Antigen tests!

I need to quote what Dr. H.T. Wickremasinghe said in his article, published in The Island of Tuesday, February 16th, 2021:

“…let me conclude, while emphasising the need to continue our general public health measures, such as wearing masks, social distancing, and avoiding crowded gatherings, to reduce the risk of contact with an infected person.

“There is no science to beat common sense.”

But…do some of our folks have this thing called COMMON SENSE!

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